7th Annual PCBC Meeting - October 13-14, 2015 (Houston Methodist Research Institute)

Online registration for the 7th Annual NHLBI Progenitor Cell Biology Consortium (PCBC) Meeting in Houston, TX (Tuesday, October 13, 2015, and Wednesday October 14, 2015), is now open. We require a picture of you and a brief description of your work for registration. These will be placed in the electronic meeting booklet on the PCBC website so colleagues with similar interests can identify you. You may use your picture or text from your Hub Site webpage.

“Fellows Only Session” will be held on Monday, October 12, 2015, 8:30 a.m. – 5:00 p.m.

Introduction to Bioinformatics and Computational Genomics for Stem Cell Biologists

The NHLBI Progenitor Cell Biology Consortium (PCBC) is offering a hands-on workshop entitled, Introduction to Bioinformatics and Computational Genomics for Stem Cell Biologists. The course will be held at Montana State University in Bozeman, Montana, beginning on Monday the 28th of September and concludes on Wednesday the 1st of October, 2015. This would be the first opportunity for a Pacific Northwest or Northern Rocky Mountain destination for a NHLBI PCBC workshop/ meeting.

CRISPR/Cas9 Genome Engineering for Human Progenitor Cell Biology and Translation Course

The NHLBI Progenitor Cell Biology Consortium is offering a hands-on workshop entitled, "CRISPR/Cas9 Genome Engineering for Human Progenitor Cell Biology and Translation", from Tuesday, September 8th to Friday, September 11th, 2015, at the Hamon Center for Regenerative Science and Medicine (CRSM), UT Southwestern Medical Center in Dallas, Texas.

La Jolla Pharmaceutical Company and Vanderbilt University Enter Exclusive Research and License Agreement Covering Novel BMP Type-I Receptor Inhibitors

Dr. Charles Hong’s group at the Vanderbilt Hub has signed a licensing agreement for clinical development of novel small molecule BMP inhibitors for rare genetic disease called fibrodysplasia ossificans progressiva, muscular dystrophy and variety of cancers that are driven by aberrant BMP signaling.  Earlier versions of BMP inhibitors that the Hong group developed, such as dorsomorphin and DMH1, have been widely used to direct differentiation of pluripotent stem cells toward cardiovascular, neuronal and other lineages.

Read more via the link below:



To provide the PCBC with a mechanism to quickly award small grants to junior faculty (less than 5 years from their appointment to Assistant Professor) research associates, fellows, postdocs, and graduate students to support a well-defined specific aim. The aim should involve at least one of the following, with priority given to proposals that incorporate two:

Notice of Intent to Publish a Funding Opportunity Announcement for NHLBI Progenitor Cell Translational Consortium (U01)

NHLBI Progenitor Cell Translational Consortium (U01)

Notice Number: NOT-HL-15-268

Key Dates
Release Date:  August 4, 2015
Estimated Publication Date of Announcement: Fall 2015
First Estimated Application Due Date: Winter 2016
Earliest Estimated Award Date: September 2016
Earliest Estimated Start Date: September 2016


Gremlin 2 Promotes Differentiation of Embryonic Stem Cells to Atrial Fate by Activation of the JNK Signaling Pathway

Top Ten Articles on the Biology of Embryonic and Induced Pluripotent Stem Cells – Journal of Stem Cells 2014-2015; Hatzopoulos Hub Site 11

Green Light for Transplantation Enhancement of Stem-Cell Engraftment in a Zebrafish Model

Leonard Zon, MD, Grousbeck Professor of Pediatric Medicine at Harvard Medical School, Investigator at Howard Hughes Medical Institute, Director of the Stem Cell Program, Children’s Hospital Boston, and colleagues have developed a novel competitive marrow transplantation system in adult zebrafish in which engraftment is measured by in vivo fluorescence imaging of the kidney — the adult haematopoietic site.

NHLBI Symposium on Cardiovascular Regenerative Medicine, September 29-30, 2015

The abstract deadline for the 6th Symposium on Cardiovascular Regenerative Medicine has been extended to Tuesday, July 28, 2015. The NHLBI encourages you to submit an abstract for this event.

Identification of Specialized Progenitor Population Committed to Forming Cardiomyocytes Exclusively

Jonathan Epstein, MD, chair of the Cell and Developmental Biology Department, Ed Morrisey, PhD, the scientific director of the Institute for Regenerative Medicine, and other colleagues from the Perelman School of Medicine at the University of Pennsylvania, of PCBC Hub Site 14 have identified a specialized progenitor population that is committed exclusively to forming cardiomyoc


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